Macrolides

This is my outline on Macrolides. I would like my focus on teaching and side effects. Thank you for your help with my project.

Macrolides are active against most gram-positive bacteria and moderately active against some gram-negative bacteria. They are used to treat mild to moderate infections.

I. Macrolides 
      a. Azithromycin (Zithromax)
      b. Clarithromycin (Biaxin)
      c. Erythromycin Base (E-Mycin
      d. Erythromycin Ethylsuccinate (EES Pediamycin)
      e. Erythromycin Stearate (Erythocin Stearate)
      f. Erythromycin IV (Erythrocin lactobionate)
II. Indications
      a. Upper and Lower Respiratory infections
      b. skin and soft tissue infections
      c. Helicobacter pylori
      d. Mycobacterial species
      e. gram positive and negative organisms
      f.  Diarrhea
      g. Pregnancy catagory B and C
      h. PNA
      i. Acute PID
      j. Intestinal amebiasis
      k. Legionnaires disease
      l. Chlamydial infection 
III. Side Effects
      a. GI disturbances
      b. Nausea/Vomiting
      c. Diarrhea
      d. Abdominal cramping
      e. Hepatotoxicity
      f. Dizziness
      g. HA
      h. fatigue
      i. colitis
      j. Candidiasis
      k. Rash 
IV. Nursing Considerations
      a. obtain speciman for C and S before first dose
      b. Give multidose oral suspension 1 hour before or 2 hours after meal
      c. Monitor patient for superinfection
      d. Monitor vital signs, urine output and lab values
V. Patient teaching
      a. Oral suspension or tablets may be taken with or without, but with full glass of water
      b. Take as perscribed
      c. Avoid excessive sunlight
      d. Report adverse reactions immediately
      e. Report loose stools or diarrhea (pseudomembranous colitis needs to be ruled out
       f. Report N/V, diarrhea, abdominal cramps and itching due to Superinfection
       g. Always use alternate forms of birth control
       h. No alcohol
VI. Routes of medications
       a. PO
       b. IV
VII. Contraindications
       a. Hypersensitivity to erythomycin or macrolides
       b. use cautiously in patients with impaired hepatic function
       c. in pregnant women
       d. Drug appears in breast milk